conductivity measurements. The results show that the Au parti- cles are well-protected by the dithiol linker molecules and do not fuse into larger un- ited. The thin film material obtained clearly exhibits nonmetallic properties(i.e., electro -hopping conductivity and optical constants very different from those of metals).
Experimental
Preparation of gold seed solution
1. Nanorods
of the reported procedures for rod formation, seedmediated growth has been by far the most efficient and popular approach. The role played by the seed particle is also critical. Furthermore, the presence of small amounts or silver nitrate during the synthesis has a dramatic effect on the final shape and crystalline structure if the particles. Citrate-capped goldnanoparticle, prepare
*’Nano’ means….
Nanometer: one billionth of a meter
Nano-: prefix comes from the Greek word for ‘dwarf’
Chemical, physical, and biological properties that differ from those of their larger, or bulk counterparts
Nanotechnology: The National Nanotechnology Initiative(NNI)-> the science of materials and phenomena in the range of 1 to 100nm in diameter
*Features of ‘nanoparticles
1.Nano
어원 : 그리스어 ‘nanos’ – 난쟁이
SI 단위계에서 10-9
1 나노미터(nm): 10억분의 1m
Nanotechnology :
Research and technology development at the atomic, molecular, or macromolecular levels, in the length scale of approximately 1~100nm range
The medical application of nanotechnology
나노물질이 갖는 특유의 성질을 질병의 진단, 치료
nanoparticles that can carry the drug molecules to the target safely.
5.2.2 Nanocarriers - Nanoparticles
Before starting with the functionalization of nanoparticles, it is important to keep in mind a range of useful properties we wish to have in any drug delivery across the BBB(Blood brain barrier). In this context, owing to their small size, customizable surface, improved solubility, tar
Nanoparticles present possible dangers
- due to the high surface to volume ratio
pass through cell membranes in organisms
Smaller nanoparticles evinced increased cytotoxicity.
Self-assembly :
process that disordered system of components forms an organized structure or pattern
The device is switched on - >
the pump pushes ions across the lipid membrane,
goldnanoparticles
Insertion of vector/nanoparticle complex into
Chloroplast genome in plant leaf
: use of “Gene Gun”
7. Growth of plant leaf material
and select successfully transformed plants
8. Development into transgenic plants
SARS 백신 생산에 실제 도입 실험
기존 핵 형질 전환법과 비교 실험
엽록체 형질 전환법과 추
~ 2000 Years Ago – Sulfide nanocrystals used by Greeks and Romans to dye hair
~ 1000 Years Ago (Middle Ages) – Goldnanoparticles of different sizes used to produce different colors in stained glass windows
1959 – “There is plenty of room at the bottom” by R. Feynman
1974 – “Nanotechnology” - Taniguchi uses the term nanotechnology for the first time
1981
가능성을 열어주고 있다.
금 나노 입자의 합성은 오랜 역사를 가지고 있다. 영국의 마이클 패러데이(Michael Faraday)는 금 나노 입자를 물에 분산시킨 금 수화졸(gold hydrosol)을 만드는 방법을 제안한 바 있고, 최근까지도 수용액 중에 금 나노 입자를 만드는 다양하고 새로운 방법이 계속 개발되어 있다.
nanoparticles-H2O2-ABTS detection system.
Keywords-microfluidic device, DNA extraction, SNP detection
I. INTRODUCTION
Single nucleotide polymorphisms (SNPs) comprise the most abundant source of genetic variation in the human genome. A SNP is a DNA sequence variation occurring when a single nucleotide — A, T, C or G — in the genome (or other shared sequence) differs between member